Paul Focke, Ph.D.

Paul Focke, Ph.D.

Technology Specialist


  • Ph.D., Neuroscience, Oregon Health and Science University, Portland, Oregon
  • B.A., Molecular Biology, University of Wisconsin-Madison, Madison, Wisconsin



  • Paul Focke provides technical consultation across a wide range of scientific and engineering fields.
  • Research experience includes protein biophysics, electron paramagnetic resonance spectroscopy, protein engineering, gene regulatory networks, neural stem cell differentiation, and molecular signal transduction.



  • Liu S, Focke PJ, Matulef K, Bian X, Moenne-Loccoz P, Valiyaveetil FI, Lockless SW, “Ion-binding properties of a K+ channel selectivity filter in different conformations”, Proc Natl Acad Sci, 112(49), 2015.
  • Focke PJ, Annen AW, Valiyaveetil FI, “Engineering the glutamate transporter homolog GltPh using protein semisynthesis”, Biochemistry, 54(8), 2015.
  • Focke PJ, Wang X, Larsson HP, “Neurotransmitter transporters: structure meets function”, Structure, 21(5), 2013.
  • Focke PJ, “Opposite movement of the external gate of a glutamate transporter homolog upon binding cotransported sodium compared with substrate”, J Neuroscience, 31(16), 2011.
  • Focke PJ, Valiyaveetil FI, “Studies of ion channels using expressed protein ligation”, Current Opinion in Chemical Biology, 14(6), 2010.